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UV-B radiation studies

The skin is in constant exposure to various external environmental stressors, including solar ultraviolet (UV) radiation. Various wavelengths of UV light are absorbed by the DNA and other molecules in the skin to cause DNA damage and induce oxidative stress. The exposure to excessive ultraviolet (UV) radiation and/or accumulation of damage over time can lead to photocarcinogenesis and photoaging.

The UV-B protective effects of different test substances are determined using zebrafish as an in vivo model.

TYPE OF ASSAYS

Acute toxicity, analysis ROS and NO production, melanin content quantification, evaluation of pigmentation, effectiveness evaluation.

Cell Regeneration studies

The regeneration of the skin occurs in a constant way, although this process is performed less quickly when aging. The regeneration process can be significantly accelerated through healthy lifestyle habits as well as the use of specific products. Ikan offers a complete analysis to evaluate the cell regeneration effects on the process of different target substances by using zebrafishh models.

TYPE OF ASSAYS

Acute toxicity in zebrafish embryos, effectiveness evaluation, aging simulation test.

Inflammation studies

Inflammatory skin diseases are the most common problem in dermatology. cute inflammation can result from exposure to UV radiation (UVR), ionizing radiation, allergens, or to contact with chemical irritants (soaps, hair dyes, etc.).

TYPE OF ASSAYS

Acute toxicity in zebrafish embryos, effectiveness evaluation, and inflammation simulation test.