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A major difficulty found in effective cancer treatment is the complexity of the biological mechanism underlying cancer onset and disease progression. This is because the genetic makeup and metabolic profile of each individual patient influence the effect of anticancer drugs. As such, different people respond differently to the same therapy: while one treatment brings about the desired success in one group of patients, it does not change the condition of other groups at all and may even leads to adverse effects.

Ikan Biotech has designed an innovated strategy for prevention and treatment of cancer called ZebraONCOfish. The chance to carry out a dynamic display of the cancerous process in vivo offers us the unique opportunity to understand this subjacent biology and design a tailor-made treatment for each case.

Type of experimental models

Orthotopic

Microinjection of tumoral cells directly into their organ of origin tends to grow better, as well as to obtain a relevant results for anti-cancer drug screening.

Tumor cell growth, invasiveness and survival, protein and RNA expression, effectiveness and sustainability of novel compounds.

Xenograft

Microinjection of tumor cells in zebrafish offers an efficient tumor model system to design and test the efficacy of potential drugs for the treatment of cancer. This model offers a wide variety of assays that are suitable for personalized therapeutics design.

Tumor cell growth, invasiveness and survival, protein and RNA expression, effectiveness and sustainability of novel compounds.

Ikan through these experimental models contribute to evaluate how our customer’s susbtances affect the carcinogenic process, metastasis, angionenesis, etc.